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Tadalafil belongs to the group of medicines called phosphodiesterase type 5 (PDE 5) inhibitors, primarily used to treat erectile dysfunction (impotence) and benign prostatic hyperplasia (BPH). Erectile dysfunction is the inability to keep a hard and erect penis suitable for sexual activity. Benign prostatic hyperplasia, also called prostate enlargement, is the non-cancerous growth of the prostate gland.

Tadalafil contains ‘Tadalafil’, which works by relaxing the blood vessels in the penis; this allows the blood to flow into the penis when the person is sexually excited. Thereby, it helps to treat erectile dysfunction. Tadalafil relaxes the bladder and prostate muscles, thereby reducing enlarged prostate symptoms such as difficulty in urination and urgent need to urinate.

You are advised to take Tadalafil for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as headache, back pain, muscle pain, pain in the legs and arms, nasal congestion, indigestion, and facial flushing. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Tadalafil if you are taking nitrates (used to treat angina), riociguat (used to treat pulmonary hypertension) or alpha-blockers; if you have heart problems or stroke, low blood pressure or uncontrolled high blood pressure. Tadalafil is not intended for use in women. Tadalafil may cause dizziness, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness. Tadalafil should not be given to children as safety and effectiveness have not been established. Keep your doctor informed about your health condition and the medicines you are taking to avoid unpleasant side effects.

Read the label of Tadalafil Inform your doctor if you have any kidney problems or heart problems, liver cirrhosis or kidney impairment, muscle problems, eye problems, mental health concerns or stomach bleeding. Tadalafil should be used along with regular exercise as it can be a strain on your stomachbelt

Tadalafil strength should not be used if you are allergic to Tadalafil or any other ingredients in the medicines. Before taking Tadalafil, tell your doctor if you are a woman. Tadalafil may also cause vaginal bleeding or had a stroke. This may be a sign of an increased risk of bleeding. If you are taking tadalafil for erectile dysfunction, avoid douch, douche or douche as these products have been shown to cause increased vaginal bleeding. You should not take this medicine if you are taking nitrates (used to treat angina). Nitrates come as tablets, sublingual tablets, vardenafil (under the brand name Viagra) and glibenclamide (usual brand name Cimziale).

Swallow Tadalafil wholeroud, with or without food. Avoid grapefruit products as they may cause a rise in Tadalafil levels and make it less effective. Tadalafil should be used with a healthy, balanced diet and regular exercise as it may reduce the effectiveness of this medicine.

Important safety information about Tadalafil:

  • The only way to truly use Tadalafil is to miss it
  • Some of the common side effects of Tadalafil are headache, indigestion, stuffy nose and flushing.
  • Some of the more serious side effects of Tadalafil are stuffy nose, headache, flushing and muscle pain. If you experience any of these symptoms, stop taking Tadalafil and contact your doctor immediately.

Do not take Tadalafil if you are taking any of the following medicines:

  • Alpha-blockers, such as alfuzosin (Uroxatral), gliclazide (Uroxatral), tamsulosin (Flomax), vardenafil (Levitra)
  • Cimetidine, Tagametrestif (Sustiva)
  • Riociguat (Adempas)
  • Alpha -mitane (or Adcirca)
  • Thrombosporea

This is not a complete list of side effects.

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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.

If you are taking Cialis or other medications for blood pressure, it is important for your healthcare provider to consider these interactions:

  • Rchecked symptoms
  • High blood pressure levels
  • addyops
  • dizziness
  • fainting

It is of the second-line treatment for individuals with a blood pressure-lowering effect.

  1. Nitrates: This medication is used to treat angina, high blood pressure, and high cholesterol in adults. It lowers blood pressure by relaxing blood vessels, which can increase the risk of heart attack or stroke in sensitive individuals.
  2. Alpha-blockers: While Cialis can enhance blood pressure-lowering effects, it is of limited blood pressure response compared to nitrates. Independent scientific evidence does not suggest a greater risk.

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Side Effects cialis tablet reviews, precautions Cialis is considered to be a safe drug. Here are some common side effects of Cialis : 1. Headache 2. Flushing 3. Dizziness 4. Headache 5. Nausea 6. Diarrhea 7. Muscle pain 8. Back pain 9. Indigestion Prevention</ side effects of Cialis are usually mild and temporary. However, if you experience serious side effects think that you may be suffering from an allergic reaction, cardiac problem, kidney problems, breathing problems, vision problems, chest pain, fast or irregular heartbeat, chest pain, fast acting fluconazole (Lanzan ) reaction, sudden numbness or weakness (rash, swelling of face, arm and body), weakness or numbness of an arm or leg, complete loss of vision, prolonged and sometimes painful erection (priapism), heart attack, etc., could be a indication of treatment with Cialis. Precautions This medication is not intended to be used to provide you with advice about whether you are suffering from a medical condition, whether you have a medical condition, or if you think you may be suffering from a medical condition. It is important to remember that while using Cialis, you should avoid drinking alcohol while taking this medication. If you have any questions contact your doctor / nurse / health advisor / local physician.

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